Hydrochloric Acid → HCID 67621026, compound

Participants

Reaction Steps

Following the procedure described in Example 120, the coupling of N-[2-(3,4,5-trimethoxyphenyl)-2-oxoethyl]-L-proline hydrochloride (250 mg, 0.69 mmol) and (R)-1-(1-naphthyl)ethylamine (0.34 mL, 2.1 mmol) provided, after treatment with HCl in Et2O, 137 mg of the hydrochloride salt of L-proline, 1-[2-(3,4,5-trimethoxyphenyl)-2-oxoethyl] (R)-1-(1-naphthyl)ethylamide as a powder.

Provenance & Evidence