Itaconic acid → (1-Benzylpyrrolidin-3-yl)methanol

HRID 2293436Notes

Reaction equation

[C:1]([OH:9])(=O)[C:2]([CH2:4][C:5](O)=O)=[CH2:3].[CH2:10]([NH2:17])[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[CH2:10]([N:17]1[CH2:5][CH2:4][CH:2]([CH2:1][OH:9])[CH2:3]1)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

Reactant 2

HCID 811Itaconic acid

HCID 7504Benzylamine

Product 1

HCID 5176654(1-Benzylpyrrolidin-3-yl)methanol

Procedure

This was prepared from itaconic acid and benzylamine by the procedure described by Feldkamp et al. J. Am. Chem. Soc.. (1961). 1519.

Sources & evidence

ORD record: ord-f82564053d414400919fe7205f5aa31d
Source dataset: uspto-grants-1997_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05686463

Reaction notes

Loading…