反应详情

A 1.00 g portion of 5-chlorosulfonyl-2,4-dimethoxybenzoic acid was added to 5 ml of saturated aqueous ammonia, followed by stirring at room temperature for 1 hour. Then, 6N hydrochloric acid aqueous solution was added to the reaction solution, and the thus precipitated product of interest was collected by filtration, washed with water and then dried under a reduced pressure to give 0.81 g of 5-aminosulfonyl-2,4-dimethoxybenzoic acid.

1. filtrationthe thus precipitated product of interest was collected by filtration
2. washwashed with water
3. customdried under a reduced pressure