反应详情

A 1.00 g portion of methyl 5-acetyl-2,4-dimethoxybenzoate was dissolved in 10 ml of methanol, and 0.24 g of sodium borohydride was added in small portions. After 10 minutes of stirring at room temperature, 1N hydrochloric acid aqueous solution was added thereto, and the thus precipitated product of interest was collected by filtration, washed with water and then dried under a reduced pressure to give 0.90 g of methyl 2,4-dimethoxy-5-(1-hydroxy)ethylbenzoate.

1. filtrationthe thus precipitated product of interest was collected by filtration
2. washwashed with water
3. customdried under a reduced pressure