Triphenylphosphine → HCID 54711645, compound

Participants

Reaction Steps

Reaction of 4-hydroxycoumarin with 3-phenyl-2-propyn-1-ol of formula I-1 in the presence of diethylazodicarboxylate and triphenylphosphine gives the compound of formula of I-2, which is partially reduced with hydrogen gas and Lindlar's catalyst to give the compound of formula I-3. Heating of the compound of formula I-3 in o-xylene at 145° C. gives the compound of formula I-4 (4-Hydroxy-3-(1-phenyl-2-propenyl)-coumarin).

Provenance & Evidence