2,6-Dichloro-4-propyl-3-pyridinamine → HCID 21477769, compound

HRID 2293704Notes

Reaction equation

HRID 2293704 reaction equation
[NH2:1][C:2]1[C:3]([Cl:12])=[N:4][C:5](Cl)=[CH:6][C:7]=1[CH2:8][CH2:9][CH3:10].[H][H]>CO.O.[Pd]>[NH2:1][C:2]1[C:3]([Cl:12])=[N:4][CH:5]=[CH:6][C:7]=1[CH2:8][CH2:9][CH3:10]

Participants

6

Reactant 2

HCID 214777682,6-Dichloro-4-propyl-3-pyridinamineHCID 178418361HCID 178418361, compound

Product 1

HCID 21477769HCID 21477769, compound

Reagents, catalysts & solvents 3

HCID 23938PalladiumCatalystHCID 887MethanolSolventHCID 962WaterSolvent

Procedure

In a 1 liter stirred autoclave 150.0 g of 3-amino-2,6-dichloro-4-n-propylpyridine and 5.0 g of 10% palladium/carbon are suspended in a mixture of 450.0 ml of methanol and 150.0 ml of water and hydrogenated under 3 bars of hydrogen at 50°-70° C. until the uptake of gas has ceased.

Sources & evidence

ORD record
ord-8f3a544454be4c91a0f45f4f3f48b7d7
Source dataset
uspto-grants-1997_11
Patent number
US05686618

Reaction notes

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