Hydrochloric Acid → HCID 21473709, compound

Participants

Reaction Steps

A solution of 0.177 g (0.00057 mol) of 2-methyl-5-(4-phenethyl-3,6-dihydro-2H-pyridin-1-ylmethyl)-pyrimidin-4-ylamine in 10 ml of ethanol was treated with 0.16 ml (0.00057 mol) of 3.5N ethanolic hydrochloric acid. The solution was completely freed from the solvents and the residue was recrystallized from methanol/diethyl ether. 0.110 g (51%) of 2-methyl-5-(4-phenethyl-3,6-dihydro-2H-pyridin-1-ylmethyl)-pyrimidin-4-ylamine dihydrochloride was obtained as white crystals; m.p. 235°-237°.

Provenance & Evidence