Hydrochloric Acid → HCID 21473697, compound

Participants

Reaction Steps

A solution of 0.077 g (0.00025 mol) of (E)-2-methyl-5-(4-styryl-3,6-dihydro-2H-pyridin-1-ylmethyl)-pyrimidin-4-ylamine in 30 ml of methanol/dichloromethane 1:1 was treated with 0.07 ml (0.00026 mol) of 3.5N ethanolic hydrochloric acid. The solution was completely freed from the solvents and recrystallized from ethanol/diethyl ether. 0.046 g (54%) of (E)-2-methyl-5-(4-styryl-3,6-dihydro-2H-pyridin-1-ylmethyl)-pyrimidin-4-ylamine hydrochloride (1:1.2) was obtained as yellowish crystals; m.p. 185°-192°.

Provenance & Evidence