Hydrochloric Acid → HCID 21473636, compound

Participants

Reaction Steps

A solution of 0.56 g (0.00053 mol) of crude 5-[6-(4-chlorophenyl)-3,4-dihydro-1H-isoquinolin-2ylmethyl]-2-methyl-pyrimidin-4-ylamine in 100 ml of ethanol was filtered and treated with 1.1 ml (0.00385 mol) of 3.5N ethanolic hydrochloric acid. The suspension obtained was suction filtered. 0.098 g (14%) of 5-[6-(4-chlorophenyl)-3,4-dihydro-1H-isochinolin-2-ylmethyl]-2-methyl-pyrimidin-4-ylamine dihydrochloride was obtained as white crystals; m.p. 223°-235° (dec).

Provenance & Evidence