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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2294112Generated: October 31, 2026

4-Benzyl-1-(2-oxazol-2-ylphenyl)piperazine → HCID 10657035, compound

https://huagongshe.com/reaction/2294112

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Benzyl-1-(2-oxazol-2-ylphenyl)piperazineHCID 10567652—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 10657035HCID 1065703573.9%

Reaction Steps

A mixture of 4-benzyl-1-(2-oxazol-2-ylphenyl)piperazine (0.906 g, 2.84 mmol) and 10% palladium on carbon (1 g) in 20 mL of methanol was stirred under a hydrogen atmosphere (1 atm) at room temperature for 4 hours. The mixture was filtered and concentrated by rotary evaporation to give 1-(2-oxazol-2-ylphenyl)piperazine (0.480 g, 2.1 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05688795
Source datasetuspto-grants-1997_11
ORD IDord-f8607d66318448df9a28b7a0260f066a
Source noteuspto-grants-1997_11