HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-N-methoxy-N-methylnicotinamide → HCID 21473428, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-N-methoxy-N-methylnicotinamide | HCID 10236076 | — |
| Reactant | 3-{4-[2-(2,2,2-Trifluoroethoxy)phenyl]piperazin-1-yl}propylamine | HCID 10567490 | — |
| Product | HCID 21473428 | HCID 21473428 | — |
Reaction Steps
substituting 3-{4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl}propylamine and 2-chloro-N-methoxy-N-methylnicotinamide gave 2-(3-{4-[2-(2,2,2-trifluoroethoxy)phenyl]piperazin-1-yl}propylamino)-N-methoxy-N -methylnicotinamide hydrochloride, m.p. 161°-177° C.; Anal.: Calcd. for C23H30F3N5 O3.(HCl)1.75.(C4H8O)0.1 : C, 55.79; H, 7.04; N, 14.78%; Found: C, 55.83; H, 6.92; N, 14.69%;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05688795 |
| Source dataset | uspto-grants-1997_11 |
| ORD ID | ord-a064cc8edaa445059a81307bd3463570 |
| Source note | uspto-grants-1997_11 |