Sodium Hydroxide → HCID 21473956, compound

Participants

Reaction Steps

9.86 ml of 0.1M NaOH were added to a solution of 200 mg (0.63 mmol) of 8-nitro-9-pyrrolidin-1-yl-2,3,5,6-tetrahydro[1,2,4]triazolo[4,3-c]quinazoline-3,5-dione and 20 ml of dimethylformamide and the mixture was stirred at room temperature for 30 min. Subsequently, the mixture was concentrated to dryness, treated 3 times with deionized water and again concentrated. The residue was dried in a high vacuum. There were obtained 193 mg (90%) of 8-nitro-9-pyrrolidin-1-yl-2,3,5,6-tetrahydro-[1,2,4]triazolo[1,5-c]quinazoline-2,5-dione as a red-brown powder.

Provenance & Evidence