HCID 9904891, compound → HCID 136395960, compound

HRID 2294190Notes

Reaction equation

HRID 2294190 reaction equation
[N:1]1([C:6]2[C:15]([N+:16]([O-:18])=[O:17])=[CH:14][C:13]3[NH:12][C:11](=[O:19])[N:10]4[NH:20][C:21](=[O:23])[N:22]=[C:9]4[C:8]=3[CH:7]=2)[CH:5]=[CH:4][N:3]=[CH:2]1>CN(C=O)C>[N:1]1([C:6]2[C:15]([N+:16]([O-:18])=[O:17])=[CH:14][C:13]3[NH:12][C:11](=[O:19])[N:22]4[C:21](=[O:23])[NH:20][N:10]=[C:9]4[C:8]=3[CH:7]=2)[CH:5]=[CH:4][N:3]=[CH:2]1

Participants

3

Reactant 1

HCID 9904891HCID 9904891, compound

Product 1

HCID 136395960HCID 136395960, compoundYield 84%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A solution of 100 mg (0.32 mmol) of 9-imidazol-1-yl-8-nitro-2,3,5,6-tetrahydro-[1,2,4]triazolo[1,5-c]quinazoline-2,5-dione and 10 ml of DMF was heated to 80° C. for 30 min. and subsequently concentrated to dryness. After trituration with acetone the residue was filtered off under suction. There were obtained 84 mg (84%) of 9-imidazol-1-yl-8-nitro-2,3,5,6-tetrahydro-[1,2,4]triazolo[4,3-c]quinazoline-3,5-dione.

Workup

  1. concentrationsubsequently concentrated to dryness
  2. filtrationAfter trituration with acetone the residue was filtered off under suction

Sources & evidence

ORD record
ord-4847d45b789b4342b71b00be0e21af77
Source dataset
uspto-grants-1997_11
Patent number
US05688803

Reaction notes

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