Hydrochloric Acid → HCID 21474381, compound

HRID 2294242Notes

Reaction equation

HRID 2294242 reaction equation
[CH2:1]([C:8]1[N:9]([CH2:16][CH2:17][O:18]C(=O)C)[CH:10]=[CH:11][C:12](=[O:15])[C:13]=1[OH:14])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl>[OH-].[Na+].C(O)C>[CH2:1]([C:8]1[N:9]([CH2:16][CH2:17][OH:18])[CH:10]=[CH:11][C:12](=[O:15])[C:13]=1[OH:14])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 21474334HCID 21474334, compound

Product 1

HCID 21474381HCID 21474381, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 14798Sodium HydroxideSolvent

Procedure

0.915 g of 2-benzyl-3-hydroxy-1-(2-acetoxy-ethyl)-1H-pyridin-4-one (Example 42) are stirred at room temperature in a mixture of 2 ml of 2N NaOH and 10 ml of ethanol for 24 hours. Then 2 ml of 2N HCl are added and the reaction mixture is stirred at room temperature for one hour, filtered and washed with cold ethanol. Drying yields 2-benzyl-3-hydroxy-1-(2-hydroxy-ethyl)-1H-pyridin-4-one.

Workup

  1. filtrationfiltered
  2. washwashed with cold ethanol
  3. customDrying

Sources & evidence

ORD record
ord-6d1f62f355e1475db1f0e16e99557b46
Source dataset
uspto-grants-1997_11
Patent number
US05688815

Reaction notes

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