HCID 21474425, compound → HCID 21474442, compound

HRID 2294253Notes

Reaction equation

HRID 2294253 reaction equation
C([O:8][C:9]1[C:14](=[O:15])[CH:13]=[CH:12][N:11]([CH3:16])[C:10]=1[CH:17]([OH:24])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][N:19]=1)C1C=CC=CC=1>ClCCl.C(O)C>[OH:8][C:9]1[C:14](=[O:15])[CH:13]=[CH:12][N:11]([CH3:16])[C:10]=1[CH:17]([OH:24])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][N:19]=1

Participants

3

Reactant 1

HCID 21474425HCID 21474425, compound

Product 1

HCID 21474442HCID 21474442, compound

Reagents, catalysts & solvents 1

HCID 21584144Dichloromethane ethanolSolvent

Procedure

3-Benzyloxy-2-(hydrox-pyridin-2-yl-methyl-1-methyl-1H-pyridin-4-one: From 2.5 g of 3-benzyloxy-1-methyl-2-[pyridin-2-yl-(tetrahydropyran-2-yloxy)-methyl]-1H-pyridin-4-one there is obtained analogously to Example 7b: 3-benzyloxy-2-(hydroxy-pyridin-2-yl-methyl)-1-methyl-1H-pyridin-4-one. Yellow resin. Rf value: 0.52 (silica gel 60, dichloromethane/ethanol 4/1).

Sources & evidence

ORD record
ord-cc58c5eb8f4c42c1865db2327d82067a
Source dataset
uspto-grants-1997_11
Patent number
US05688815

Reaction notes

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