Azobisisobutyronitrile → HCID 22349221, compound

HRID 229440Notes

Reaction equation

HRID 229440 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([C:8]2[O:12][C:11]([P:13]([O:18][CH2:19][CH3:20])(=[O:17])[O:14][CH2:15][CH3:16])=[CH:10][CH:9]=2)[CH:5]=[CH:6][CH:7]=1.C1C(=O)N([Br:28])C(=O)C1.CC(N=NC(C#N)(C)C)(C#N)C>C(Cl)(Cl)(Cl)Cl>[Br:28][C:7]1[CH:6]=[CH:5][C:4]([C:8]2[O:12][C:11]([P:13]([O:18][CH2:19][CH3:20])(=[O:17])[O:14][CH2:15][CH3:16])=[CH:10][CH:9]=2)=[CH:3][C:2]=1[NH2:1]

Participants

5

Reactant 3

HCID 6547AzobisisobutyronitrileHCID 67184N-bromobutanimideHCID 22349231HCID 22349231, compound

Product 1

HCID 22349221HCID 22349221, compound

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent

Procedure

A mixture of diethyl 5-(3-aminophenyl)-2-furanphosphonate (1 mmol), NBS (0.9 mmol) and AIBN (0.1 mmol) in 30 mL of CCl4 was stirred at rt for 2 h. Extraction and chromatography provided diethyl 5-(4-bromo-3-aminophenyl)-2-furanphosphonate as an oil.

Workup

  1. extractionExtraction and chromatography

Sources & evidence

ORD record
ord-a70d44db0c574eb3a439bcbe9439de2b
Source dataset
uspto-grants-2009_07
Patent number
US07563774B2

Reaction notes

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