反应详情

3.1 g (15 mmol) of the allyl ester obtained above in (a), 20 ml of methyl alcohol and 20 ml of THF are introduced into a round-bottomed flask. While cooling in an icebath, 285 mg (7.5 mmol) of sodium borohydride are added in small portions and the mixture is stirred at room temperature for one hour. The reaction medium is poured into water, the mixture is extracted with ethyl ether and the organic phase is separated after settling has taken place, then dried over magnesium sulphate and evaporated. 3.1 g (100%) of the expected product are collected in the form of a colorless oil.

1. additionare introduced into a round-bottomed flask
2. additionare added in small portions
3. extractionthe mixture is extracted with ethyl ether
4. customthe organic phase is separated after settling
5. dry with materialdried over magnesium sulphate
6. customevaporated
7. custom3.1 g (100%) of the expected product are collected in the form of a colorless oil