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HRID229466

反应详情

EQUATION

反应方程式

HRID 229466 的结构方程式

REACTANTS

反应物

2
结构：CCC(C)(C)C(=O)CBr
HCID12822307

1-Bromo-3,3-dimethylpentan-2-one

C7H13BrO

结构：COc1ccc2c(C(OP(=O)(OC)OC)=C3CCCC3)n[nH]c2c1
HCID68850940

未命名化合物

PRODUCTS

生成物

1
结构：CCC(C)(C)C(=O)Cn1nc(C(OP(=O)(OC)OC)=C2CCCC2)c2ccc(OC)cc21
HCID68852053

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from cyclopentylidene(6-methoxy-1H-indazol-3-yl)methyl dimethyl phosphate from Step B Example 6 and 1-Bromo-3,3-dimethylpentan-2-one from Step A Example 4 using the procedure described in Method I Step C of Example 1 followed by RP-HPLC purification using 35˜100% MeCN gradient without TFA. It was obtained as a colorless solid after lyophilization. LC-MS: 3.70 min. (m/Z=339.2, 465.2, 487.1).

WORKUP

后处理

  1. customfollowed by RP-HPLC purification
  2. customIt was obtained as a colorless solid after lyophilization
  3. custom3.70 min. (m/Z=339.2, 465.2, 487.1)