反应详情

3.17 g (0.01M) of 2-(m-chlorobenzamido)-2-(p-tolyl)propionic acid was dissolved in 30 ml of acetic anhydride and the resulting solution was heated for 1 hr with reflux. The reaction solution was cooled and distilled out acetic anhydride in vacuo. The residue was subjected to chromatography, to give 2.4 g of the object compound, pure oily compound: 80 % Yield.

1. temperaturethe resulting solution was heated for 1 hr
2. temperaturewith reflux
3. temperatureThe reaction solution was cooled
4. distillationdistilled out acetic anhydride in vacuo