2-Fluorobenzylic alcohol → HCID 17989813, compound

HRID 229486Notes

Reaction equation

HRID 229486 reaction equation
[F:1][C:2]1[CH:9]=[CH:8][CH:7]=[CH:6][C:3]=1[CH2:4][OH:5].[ClH:10].[NH2:11][CH2:12][C:13](=[O:19])[CH2:14][CH2:15][C:16](O)=[O:17]>>[ClH:10].[NH2:11][CH2:12][C:13](=[O:19])[CH2:14][CH2:15][C:16]([O:5][CH2:4][C:3]1[CH:6]=[CH:7][CH:8]=[CH:9][C:2]=1[F:1])=[O:17]

Participants

3

Reactant 2

HCID 679692-Fluorobenzylic alcoholHCID 123608Aminolevulinic Acid Hydrochloride

Product 1

HCID 17989813HCID 17989813, compound

Procedure

From 2-fluorobenzyl alcohol (5.7 g; 45 mmol) and 5-amino-4-oxopentanoic acid hydrochloride (1.0 g; 6.0 mmol). The reaction was complete after 27 h at 100° C. The yield was 0.64 g (44%). Mp 91-94° C. (dec.)

Sources & evidence

ORD record
ord-1ff243290f144ce7a854d10249014356
Source dataset
uspto-grants-2009_07
Patent number
US07563819B1

Reaction notes

Loading…