4-Chlorobenzyl alcohol → HCID 17989815, compound

HRID 229489Notes

Reaction equation

HRID 229489 reaction equation
[Cl:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][OH:7])=[CH:4][CH:3]=1.Cl.[NH2:11][CH2:12][C:13](=[O:19])[CH2:14][CH2:15][C:16](O)=[O:17]>>[ClH:1].[NH2:11][CH2:12][C:13](=[O:19])[CH2:14][CH2:15][C:16]([O:7][CH2:6][C:5]1[CH:8]=[CH:9][C:2]([Cl:1])=[CH:3][CH:4]=1)=[O:17]

Participants

3

Reactant 2

HCID 133974-Chlorobenzyl alcoholHCID 123608Aminolevulinic Acid Hydrochloride

Product 1

HCID 17989815HCID 17989815, compound

Procedure

From 4-chlorobenzyl alcohol (5.0 g; 35 mmol) and 5-amino-4-oxopentanoic acid hydrochloride (1.0 g; 6.0 mmol). The reaction was complete after 24 h at 100° C. The yield was 0.56 g (32%). Mp 127-129° C.

Sources & evidence

ORD record
ord-e1bc00a2cf964756a7f430bd347e9557
Source dataset
uspto-grants-2009_07
Patent number
US07563819B1

Reaction notes

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