HCID 10698227, compound → HCID 10840687, compound

Participants

Reaction Steps

To a mixture of 4,4-bis(4-(2-quinolylmethoxy)phenyl)cyclohexanol (resulting from Example 4) (1.13 g, 2 mmol) and molecular sieves (3 g) in CH2 Cl2 (40 mL) was added PCC (0.65 g, 3 mmol) and the resulting mixture was stirred at room temperature for 30 min. The mixture was filtered through the Celite, the filtrate was concentrated in vacuo to 10 mL and then chromatographed (silica gel, 4:1 CH2Cl2 /EtOAc) to afford 0.25 g of 4,4-bis(4-(2-quinolylmethoxy) phenyl)cyclohexanone.

Provenance & Evidence