Hydrazine hydrate (1:1) → HCID 54417124, compound

HRID 2295008Notes

Reaction equation

HRID 2295008 reaction equation
[CH2:1]([C:3](=[CH:18][CH:19]([CH3:21])[CH3:20])[CH:4]=[CH:5][CH2:6][N:7]1C(=O)C2=CC=CC=C2C1=O)[CH3:2].O.NN>C(O)C>[CH2:1]([C:3](=[CH:18][CH:19]([CH3:20])[CH3:21])[CH:4]=[CH:5][CH2:6][NH2:7])[CH3:2]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 54211318HCID 54211318, compound

Product 1

HCID 54417124HCID 54417124, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of N-(4-ethyl-6-methyl-2,4-heptadiene-1-yl)phthalimide (17.62 g), hydrazine monohydrate (9.9 g), and ethanol (700 ml) was refluxed for 90 minutes under nitrogen atmosphere. The reaction mixture was evaporated in vacuo. The residue was dissolved in 10% aqueous potassium carbonate solution and extracted with ethyl acetate. The organic extract was washed with brine, dried over anhydrous magnesium sulfate, and evaporated to give 4-ethyl-6-methyl-2,4-heptadiene-1-ylamine as an oil.

Workup

  1. temperaturewas refluxed for 90 minutes under nitrogen atmosphere
  2. customThe reaction mixture was evaporated in vacuo
  3. dissolutionThe residue was dissolved in 10% aqueous potassium carbonate solution
  4. extractionextracted with ethyl acetate
  5. extractionThe organic extract
  6. washwas washed with brine
  7. dry with materialdried over anhydrous magnesium sulfate
  8. customevaporated

Sources & evidence

ORD record
ord-e7713d92fafa4cbab37fa0af2be800af
Source dataset
uspto-grants-1997_11
Patent number
US05691366

Reaction notes

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