Water → HCID 86070143, compound

Temperature

40 °C

116 parts of methoxypivalaldehyde were dissolved in 600 parts of ethanol, and a solution of 76.5 parts of hydroxylamine hydrochloride and 86 parts of sodium acetate in 500 parts of water was added dropwise to the above, vigorously stirred solution, the temperature increasing temporarily to 40° C. Stirring was continued for 24 hours at room temperature, after which the mixture was poured into 4,000 parts of water and then saturated with sodium chloride and extracted with eight times 400 parts of ether. The combined extracts were dried over sodium sulfate, the solvent was stripped off, and the residue was distilled, giving 90.4 parts of methoxypivalaldoxime as a colourless liquid at 48°-49° C./0.1 mbar. Yield: 69% of theory.

1. extractionsaturated with sodium chloride and extracted with eight times 400 parts of ether
2. dry with materialThe combined extracts were dried over sodium sulfate
3. distillationthe residue was distilled

ORD record

ord-c1c42d85e32640de892dfea7f2bc8e63

Source dataset

uspto-grants-1984_01

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US04424215