HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl chloroformate → 5,11-dihydro-11-methoxycarbonyl-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl chloroformate | HCID 6586 | — |
| Reactant | 5,11-Dihydro-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one | HCID 70169 | — |
| Solvent | Toluene | HCID 1140 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 5,11-dihydro-11-methoxycarbonyl-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one | HCID 13271738 | — |
Reaction Steps
From 5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one and methyl chlorocarbonate in a mixture of dioxan and toluene, 5,11-dihydro-11-methoxycarbonyl-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one was obtained, m.p. 266°-267° C. (D) (from 1,2-dichloroethane);
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04424222 |
| Source dataset | uspto-grants-1984_01 |
| ORD ID | ord-36ff84d6262f4dc2a2913fe901010478 |
| Source note | uspto-grants-1984_01 |