Hydrochloric Acid → HCID 20475065, compound

Participants

Reaction Steps

1 g of 5,11-dihydro-11-[[(4-methyl-1-piperazinyl)amino]carbonyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one was dissolved in a little ethanol and mixed with ethanolic hydrochloric acid. The mixture was concentrated greatly by evaporation and then acetone was added. The precipitate was recrystallized from ethanol. After air-drying 0.8 g of 5,11-dihydro-11-[[(4-methyl-1-piperazinyl)amino]carbonyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one hydrochloride hydrate were obtained;

Provenance & Evidence