HCID 20282957, compound → HCID 20282951, compound

HRID 2295420Notes

Reaction equation

HRID 2295420 reaction equation
C([O:8][C:9]1[CH:22]=[CH:21][C:12]2[CH:13]=[C:14]([C:16]([O:18][CH2:19][CH3:20])=[O:17])[O:15][C:11]=2[C:10]=1[CH2:23][CH2:24][CH3:25])C1C=CC=CC=1.[H][H]>C(OCC)(=O)C.[Pd]>[OH:8][C:9]1[CH:22]=[CH:21][C:12]2[CH:13]=[C:14]([C:16]([O:18][CH2:19][CH3:20])=[O:17])[O:15][C:11]=2[C:10]=1[CH2:23][CH2:24][CH3:25]

Participants

5

Reactant 2

HCID 20282957HCID 20282957, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 20282951HCID 20282951, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

The ester product of step (d) was dissolved in ethyl acetate and reduced under hydrogen with palladium/charcoal catalyst until uptake of hydrogen was complete. The solution was filtered and evaporated to leave ethyl 6-hydroxy-7-propylbenzofuran-2-carboxylate (2.8 g) as a pink solid.

Workup

  1. filtrationThe solution was filtered
  2. customevaporated

Sources & evidence

ORD record
ord-3f6d0a74b2a44864b3e9905d825266d1
Source dataset
uspto-grants-1984_01
Patent number
US04424231

Reaction notes

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