2,6-Dimethylaniline → HCID 22973868, compound

HRID 2295505Notes

Reaction equation

HRID 2295505 reaction equation
[CH3:1][C:2]1[CH:8]=[CH:7][CH:6]=[C:5]([CH3:9])[C:3]=1[NH2:4].[C:10]([O:15][CH3:16])(=[O:14])[C:11]([CH3:13])=O>C1C=CC=CC=1.[Cl-].[Cl-].[Zn+2]>[CH3:13][C:11](=[N:4][C:3]1[C:5]([CH3:9])=[CH:6][CH:7]=[CH:8][C:2]=1[CH3:1])[C:10]([O:15][CH3:16])=[O:14]

Participants

5

Reactant 2

HCID 68962,6-DimethylanilineHCID 11748Methyl pyruvate

Product 1

HCID 22973868HCID 22973868, compound

Reagents, catalysts & solvents 2

HCID 3007855ZincchlorideCatalystHCID 241BenzeneSolvent

Procedure

A solution of 2,6-dimethyl aniline (37.2 ml; 0.3 mol) in benzene (200 ml) was added with 0.5 g of ZnCl2, and, dropwise at room temperature, with 33.2 ml (0.33 mol) of methyl pyruvate.

Workup

  1. customdropwise at room temperature

Sources & evidence

ORD record
ord-b3396256092047889ed8b73b072dcc3c
Source dataset
uspto-grants-1984_01
Patent number
US04425357

Reaction notes

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