HCID 13245938, compound → 3-Amino-2-methylphenylmethyl acetate

HRID 2295860Notes

Reaction equation

HRID 2295860 reaction equation
[C:1]([O:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([N+:12]([O-])=O)[C:7]=1[CH3:15])(=[O:3])[CH3:2]>CO.[Pd]=O>[C:1]([O:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([NH2:12])[C:7]=1[CH3:15])(=[O:3])[CH3:2]

Participants

4

Reactant 1

HCID 13245938HCID 13245938, compound

Product 1

HCID 132459393-Amino-2-methylphenylmethyl acetateYield 97.6%

Reagents, catalysts & solvents 2

HCID 5083724Palladium monoxideCatalystHCID 887MethanolSolvent

Procedure

Using a Parr hydrogenator, 30.0 g (0.143 mol) of 2-methyl-3-nitrophenylmethyl acetate in 250 mL of methanol was hydrogenated in the presence of 0.5 g of palladium oxide on charcoal to give 25.0 g of 3-amino-2-methylphenylmethyl acetate.

Sources & evidence

ORD record
ord-090f8b7257e2476daa512f9ec917b9f2
Source dataset
uspto-grants-1984_01
Patent number
US04426524

Reaction notes

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