Methylamine → 1-Nitro-2-methylamino-2-[4-(3-methoxy-2-pyridyl)butylamino]ethylene

HRID 2295889Notes

Reaction equation

[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]1[C:11]([O:12][CH3:13])=[CH:10][CH:9]=[CH:8][N:7]=1.CS[C:16](S(C)=O)=[CH:17][N+:18]([O-:20])=[O:19].[CH3:24][NH2:25]>>[N+:18]([CH:17]=[C:16]([NH:25][CH3:24])[NH:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]1[C:11]([O:12][CH3:13])=[CH:10][CH:9]=[CH:8][N:7]=1)([O-:20])=[O:19]

Participants

Reactant 3

HCID 6329Methylamine

HCID 130600284-(3-Methoxypyridin-2-yl)butan-1-amine

HCID 544870941-Nitro2-methylthio-2-methylsulphinylethylene

Product 1

HCID 705110111-Nitro-2-methylamino-2-[4-(3-methoxy-2-pyridyl)butylamino]ethylene

Procedure

Reaction of 2-(4-aminobutyl)-3-methoxypyridine with 1-methylthio-1-methylsulphinyl-2-nitroethylene and treatment of the product with methylamine according to the general procedure of Example 2 gives 1-nitro-2-methylamino-2-[4-(3-methoxy-2-pyridyl)butylamino]ethylene.

Sources & evidence

ORD record: ord-64d1d50ff2594519a536a4549bff491e
Source dataset: uspto-grants-1984_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04426526

Reaction notes

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