HCID 86738654, compound → HCID 67880269, compound

Participants

Reaction Conditions

Reaction Steps

A suspension of 5.2 g of 11β-(acetyloxy)-17,17-bis(ethylthio)-9-fluoroandrosta-1,4-dien-3-one in 85 ml of dry diethylbenzene was stirred at 180° C. (oil bath temperature) for 1.0 hour; the suspension gradually became a homogeneous solution during the heating. The resulting solution was cooled to 0° C. and the solid that precipitated was filtered and dried in vacuo to give 3.6 g of the title compound, melting point 211°-214° C.

Provenance & Evidence