HCID 23048576, compound → HCID 20472082, compound

HRID 2296251Notes

Reaction equation

HRID 2296251 reaction equation
[CH3:1][CH:2]([CH:6]([CH3:10])[CH2:7][C:8]#[N:9])[CH2:3][C:4]#[N:5]>C1(C)C=CC=CC=1>[C:4]([C:3]1[CH:2]([CH3:1])[CH:6]([CH3:10])[CH2:7][C:8]=1[NH2:9])#[N:5]

Participants

3

Reactant 1

HCID 23048576HCID 23048576, compound

Product 1

HCID 20472082HCID 20472082, compoundYield 94.1%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

5.6 g of potassium tert.butylate are refluxed for 60 minutes with 6.8 g of 3,4-dimethyladiponitrile in 50 ml of toluene. The cooled solution is washed with 50 ml of water and concentrated. There are obtained 6.4 g (94%) of 2-cyano-3,4-dimethyl-cyclopent-1-enylamine of melting point 92°-100° C.

Workup

  1. washThe cooled solution is washed with 50 ml of water
  2. concentrationconcentrated

Sources & evidence

ORD record
ord-562c1bbe62104d11b2ed7b6247ba9656
Source dataset
uspto-grants-1984_01
Patent number
US04428886

Reaction notes

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