3-(Trifluoromethyl)phenol → HCID 12848948, compound

Participants

Reaction Conditions

Reaction Steps

215 g (1 mole) of 3,3-bisfluoromethyl-1-bromobutan-2-one were added dropwise to a stirred mixture of 162 g (1 mole) of 3-trifluoromethylphenol and 180 g (1.3 moles) of powdered potassium carbonate in 1,200 ml of acetone at 20° to 30° C. The mixture was stirred at 50° C. for 6 hours the inorganic salt was filtered off and the filtrate was concentrated. The residue was distilled under a high vacuum. 210 g of 3,3-bisfluoromethyl-1-(3-trifluoromethylphenoxy)-butan-2-one of boiling point 114°-18° C./0.6 mm Hg were obtained. ##STR10##

Provenance & Evidence