HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 70514525, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 4-Amino-5-propylthiophene-3-carboxylic acid | HCID 13286158 | — |
| Product | HCID 70514525 | HCID 70514525 | — |
Reaction Steps
A sample of 1.50 g. (8.097 mmols) of 4-amino-5-propyl-3-thiophenecarboxylic acid was dissolved in 75 ml. absolute ethanol which had been previously saturated with gaseous hydrogen chloride. The resulting reaction was heated under reflux for 24 hours, cooled and evaporated to afford 1.43 g. (71%) of pure 4-amino-5-propyl-3-thiophenecarboxylic acid ethyl ester hydrochloride, m.p. 144° C. (dec.) after recrystallization from ethyl acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04428963 |
| Source dataset | uspto-grants-1984_01 |
| ORD ID | ord-d4d7f0fe0b3a4170ade8d319d8eadb8a |
| Source note | uspto-grants-1984_01 |