Diphenyl Ether → HCID 13060557, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of dimethyl [[6-cyclohexanecarboxamido-4-quinazolinylamino]methylene]propanedioate (4 g) and diphenyl ether (31 ml) was stirred at 260° C. for 15 minutes. After cooling to ambient temperature, the resulting solid was collected by filtration, washed with hexane and dried. There was obtained methyl 4-oxo-10-cyclohexanecarboxamido-4H-pyrimido[1,2-C]quinazoline-3-carboxylate (3.6 g).

Provenance & Evidence