Hydrochloric Acid → 3,5-Dichloroaniline

Participants

Reaction Steps

200 parts of phenol, 131 parts of a tetrachloroaniline/pentachloroaniline mixture corresponding to the composition mentioned in Example 3, 1 part of ruthenium-on-charcoal catalyst (5% strength) which has already been used for 10 previous similar experiments, and 12 parts of aqueous hydrochloric acid (57% strength) are reacted in a tantalum autoclave, during the course of 3.5 hours at 165° C., whilst stirring, at a hydrogen pressure of 50 bars. After the usual working up, 90 parts of 99% strength 3,5-dichloroaniline are isolated. Yield: 97% of theory.

Provenance & Evidence