HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Amino-6-nitro-4(3H)-quinazolinone → HCID 135813643, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Amino-6-nitro-4(3H)-quinazolinone | HCID 135813642 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 135813643 | HCID 135813643 | 98.5% |
Reaction Steps
A suspension of the above amine (250 mg, 1.21 mmol) in MeOH (50 mL) was hydrogenated over 10% Pd/C (50 mg) at 50 psi for 5 h. The catalyst was removed by filtration and the filtrate concentrated to yield 5,6-diaminoquinazolin-4-one (210 mg, 98% crude).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06489328B2 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-bd5e130e88eb46dabd5e0f3d31341743 |
| Source note | uspto-grants-2002_12 |