HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylbenzoyl chloride → 2-(2-Hydroxyethyl)-5-[4-(2-methylbenzoylamino)benzene-sulfonyl]-1,5-benzothiazepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylbenzoyl chloride | HCID 70276 | — |
| Reactant | [1,1'-Biphenyl]-2-carbonyl chloride | HCID 12563768 | — |
| Reactant | 2-(2-Hydroxyethyl)-5-(4-aminobenzenesulfonyl)-1,5-benzothiazepine | HCID 18387437 | — |
| Product | 2-(2-Hydroxyethyl)-5-[4-(2-methylbenzoylamino)benzene-sulfonyl]-1,5-benzothiazepine | HCID 18387430 | — |
Reaction Steps
Compound 4 as prepared in Example 25 (0.55 g, 1.5 mM) was treated as described in Example 26 with 2-toluoyl chloride (0.3 ml) substituted for 2-phenylbenzoyl chloride to give the desired product m/z (MH+)483
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06489321B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-4c8fa763d08c426892ed575af4db55e4 |
| Source note | uspto-grants-2002_12 |