Benzoyl chloride, 3,4-dichloro- → 2-(2-Hydroxyethyl)-5-[4-(3,4-dichlorobenzoylamino)benzene-sulfonyl]-1,5-benzothiazepine

Participants

Role	Name	HCID	Charge
Reactant	Benzoyl chloride, 3,4-dichloro-	HCID 76403	—
Reactant	[1,1'-Biphenyl]-2-carbonyl chloride	HCID 12563768	—
Reactant	2-(2-Hydroxyethyl)-5-(4-aminobenzenesulfonyl)-1,5-benzothiazepine	HCID 18387437	—
Product	2-(2-Hydroxyethyl)-5-[4-(3,4-dichlorobenzoylamino)benzene-sulfonyl]-1,5-benzothiazepine	HCID 18387470	—

Reaction Steps

Compound 4 as prepared in Example 25 was treated as described in Example 26 with 3,4-dichlorobenzoyl chloride (0.085 g, 0.41 mM) substituted for 2-phenylbenzoyl chloride to give the product. m/z (MH+)537

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06489321B1
Source dataset	uspto-grants-2002_12
ORD ID	ord-ef539328838a43a8bcafe86911299cac
Source note	uspto-grants-2002_12