HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 18388574, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Bromoacetamide | HCID 69632 | — |
| Reactant | HCID 86585197 | HCID 86585197 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 18388574 | HCID 18388574 | 141.8% |
Reaction Steps
Bis-TFA 1,4,7-triazacyclononane (261.4 mg, 0.81 mmol) was dissolved in acetonitrile (5.0 mL), bromoacetamide (168.1 mg, 1.22 mmol) and K2CO3 (225.0 mg, 1.62 mmol) were added sequentially. The mixture was refluxed for 15 hours. Filtration and chromatography of the residue after removal of all volatiles gave the desired product as an oil (214.0 mg, 70%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06489472B2 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-6225828c98e741e7be9ce2ef4190ed29 |
| Source note | uspto-grants-2002_12 |