HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2297024Generated: November 2, 2026
4-Methoxy-2-aminobenzothiazole → 2-Amino-4-hydroxybenzothiazole
https://huagongshe.com/reaction/2297024
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Methoxy-2-aminobenzothiazole | HCID 21622 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Solvent | Ethanethiol | HCID 6343 | — |
| Product | 2-Amino-4-hydroxybenzothiazole | HCID 24057 | — |
Reaction Steps
A solution of AlCl3 (5 mmole) in EtSH (10 mL) was cooled to 0° C. and treated with 2-amino-4-methoxybenzothiazole (1 mmole). The mixture was stirred at 0-5° C. for 2 h. Evaporation and extraction gave 2-amino-4-hydroxybenzothiazole as white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06489476B1 |
|---|
| Source dataset | uspto-grants-2002_12 |
|---|
| ORD ID | ord-19fed726a11443f3972e553b933a70a5 |
|---|
| Source note | uspto-grants-2002_12 |
|---|
