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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2297078Generated: November 1, 2026

2-Tert-Butylphenol → Cyclohexanol, 2-(1,1-dimethylethyl)-, (1R,2R)-rel-

https://huagongshe.com/reaction/2297078

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Tert-ButylphenolHCID 6923—
Reactant2-tert-Butylcyclohexyl acetateHCID 62334—
ReactantHCID 178418361HCID 178418361—
ProductCyclohexanol, 2-(1,1-dimethylethyl)-, (1R,2R)-rel-HCID 6995536—

Reaction Steps

A pressurized container fitted with stirrer is charged with 2-tertiary-butylphenol, 2-tertiary-butylcyclohexyl acetate and the catalyst. Hydrogenation is carried out at the chosen reaction temperature and hydrogen pressure. The resulting cis-2-tertiary-butylcyclohexanol is obtained following removal of the catalyst by filtration, decantation or centrifugation.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06489520B2
Source datasetuspto-grants-2002_12
ORD IDord-5d06102f987e48c39d6f408953fbfe37
Source noteuspto-grants-2002_12