HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2,4-Dichlorophenyl)-2-morpholin-4-ylethan-1-one → (2e)-1-(2,4-Dichlorophenyl)-3-(dimethylamino)-2-morpholin-4-ylprop-2-en-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2,4-Dichlorophenyl)-2-morpholin-4-ylethan-1-one | HCID 22142875 | — |
| Solvent | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Product | (2e)-1-(2,4-Dichlorophenyl)-3-(dimethylamino)-2-morpholin-4-ylprop-2-en-1-one | HCID 69308798 | — |
Reaction Steps
1 mmol of 1-(2,4-dichlorophenyl)-2-morpholin-4-ylethan-1-one was heated to 80° C. in N,N-dimethylformamidedimethyl acetal for six hours. The reaction mixture was concentrated in vacuo and purified by trituration: with diethyl ether to obtain (2E)-1-(2,4-dichlorophenyl)-3-(dimethylamino)-2-morpholin-4-ylprop-2-en-1-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06489344B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-60d03fea7b2c45e39fe5a413034a728e |
| Source note | uspto-grants-2002_12 |