HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → 6-chloro-N-methyl-3-nitropyridin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 6-Chloro-2-dimethylamino-3-nitropyridine | HCID 21787625 | — |
| Product | 6-chloro-N-methyl-3-nitropyridin-2-amine | HCID 10750094 | — |
Reaction Steps
6-chloro-2-methylamino-3-nitro-pyridine was prepared in accordance to the procedure described above for the preparation of 6-chloro-2-dimethylamino-3-nitro pyridine by using solution of methyl amine. The crude product was purified by flash chromatography, eluting with 90% hexane: 10% ethyl acetate to 16 (300 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06489344B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-007012c06bae43de971176a8f4bd75bb |
| Source note | uspto-grants-2002_12 |