1-Bromooctane → HCID 18381097, compound

HRID 2297341Notes

Reaction equation

HRID 2297341 reaction equation
[F:1][C:2]1[C:3]([C:21]2[CH:26]=[CH:25][C:24]([OH:27])=[CH:23][CH:22]=2)=[C:4]2[C:9](=[CH:10][C:11]=1[F:12])[CH2:8][CH:7]([CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])[CH2:6][CH2:5]2.[CH2:28](Br)[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35]>CCOCC>[F:1][C:2]1[C:3]([C:21]2[CH:22]=[CH:23][C:24]([O:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35])=[CH:25][CH:26]=2)=[C:4]2[C:9](=[CH:10][C:11]=1[F:12])[CH2:8][CH:7]([CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])[CH2:6][CH2:5]2

Participants

4

Reactant 2

HCID 81401-BromooctaneHCID 18381133HCID 18381133, compound

Product 1

HCID 18381097HCID 18381097, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

From 6,7-difluoro-5-(4-hydroxyphenyl)-2-octyl-1,2,3,4-tetrahydronaphthalene and 1-octyl bromide by means of the Williamson ether synthesis.

Sources & evidence

ORD record
ord-272669a6dabf49e789684ddb35256713
Source dataset
uspto-grants-2002_12
Patent number
US06491989B1

Reaction notes

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