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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2297352Generated: October 25, 2026

2,3-Epoxyhexanol → 5-Hexyloxy-2-[1,6,7-trifluoro-5-(3-propyloxiranylmethoxy)naphthalen-2-yl]-pyrimidine

https://huagongshe.com/reaction/2297352

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-EpoxyhexanolHCID 543565—
Reactant2,3,5-Trifluoro-6-(5-hexyloxypyrimidin-2-yl)naphthalen-1-olHCID 18381124—
Product5-Hexyloxy-2-[1,6,7-trifluoro-5-(3-propyloxiranylmethoxy)naphthalen-2-yl]-pyrimidineHCID 18381106—

Reaction Steps

From 2,3,5-trifluoro-6-(5-hexyloxypyrimidin-2-yl)naphthalen-1-ol and (3-propyloxiranyl)methanol by means of the Mitsunobu reaction.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06491989B1
Source datasetuspto-grants-2002_12
ORD IDord-c9b5c5fa426b45c9962e15c4facf74ea
Source noteuspto-grants-2002_12