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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2297355Generated: October 29, 2026

2,3-Epoxyhexanol → 2-[6,7-Difluoro-5-(3-propyloxiranylmethoxy)naphthalen-2-yl]-5-hexyloxypyrimidine

https://huagongshe.com/reaction/2297355

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-EpoxyhexanolHCID 543565—
Reactant2,3-Difluoro-6-(5-hexyloxypyrimidin-2-yl)naphthalen-1-olHCID 15405319—
Product2-[6,7-Difluoro-5-(3-propyloxiranylmethoxy)naphthalen-2-yl]-5-hexyloxypyrimidineHCID 15405320—

Reaction Steps

From 2,3-difluoro-6-(5-hexyloxypyrimidin-2-yl)naphthalen-1-ol and (3-propyloxiranyl)methanol by means of the Mitsunobu reaction.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06491989B1
Source datasetuspto-grants-2002_12
ORD IDord-1e6aaef641f14c1ca74ffadd2fd59d32
Source noteuspto-grants-2002_12