HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 69831222, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 3,5-Dichloro-4-methylpyridine | HCID 10953827 | — |
| Reactant | HCID 53820011 | HCID 53820011 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 69831222 | HCID 69831222 | 40.4% |
Reaction Steps
Operating analogously to what described in example 15 starting from 1-chloro-6-methoxy-5-pyridin-4-ylethynyl-phthalazine (1.38 g, 4.66 mmoles), prepared as described in example 142, 3,5-dichloro-4-methylpyridine (1.887 mg, 11.65 mmoles), DMF (20 ml), NaH (466 mg, 11.65 mmoles), 793 mg of the title compound were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06492360B1 |
| Source dataset | uspto-grants-2002_12 |
| ORD ID | ord-c5b0ffe83d314876bcad5a5848c77e5d |
| Source note | uspto-grants-2002_12 |