Tetrahydrofuran → HCID 86758638, compound

Participants

Reaction Steps

Isatoic anhydride (4.5 g), 3-aminopropanol (2.66 ml) were added to tetrahydrofuran (70 ml), and the mixture was stirred at room temperature for 4 hours. Tetrahydrofuran was removed and the residue was purified by silica gel column chromatography (ethyl acetate) to obtain 4.7 g of N-(4-hydroxybutyl)(2-aminophenyl)formamide. Yield: 82%.

Provenance & Evidence