4-N-Propylbenzenesulphonyl chloride → HCID 18382269, compound

Participants

Reaction Steps

Similarly to Example 1, reaction of 2-[4-(5-methyl-[1,2,4]oxadiazol-3-yl)phenyl]-1-piperazin-1-ylethan-1-one (“B”) and 4-propylphenylsulphonyl chloride gives the compound 1-[4-(4-propylphenylsulphonyl)piperazin-1-yl]-2-[4-(5-methyl-[1,2,4]oxadiazol-3-yl)phenyl]ethan-1-one and, after hydrogenation, 4-{2-oxo-2-[4-(4-propylphenylsulphonyl)piperazin-1-yl]ethyl}benzamidine, FAB 429.

Provenance & Evidence